Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19237535 | 0.81 | S1PR4 (0.47) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL10028047 | 0.79 | HPGD (0.53) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL19785375 | 0.78 | HSP90AA1 (0.56) | MAPTALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL19243070 | 0.77 | S1PR4 (0.42) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL266467 | 0.72 | PTPN1 (0.47) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL18551784 | 0.71 | GSK3B (0.56) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL14363094 | 0.71 | L3MBTL1 (0.50) | MAPTALDH1A1KDM4ETSHRGSK3B | |
| SCHEMBL13680560 | 0.71 | GSK3B (0.59) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL1616485 | 0.71 | ALDH1A1 (0.53) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL7777278 | 0.71 | HSP90AA1 (0.50) | SMN1; SMN2KDM4ENPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9751897-B1 | Derivatives of Bodipy | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2017-09-05 | — | — | US | disclosed |
| WO-2017139689-A1 | DERIVATIVES OF BODIPY | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2017-08-17 | — | — | WO | disclosed |
| US-20170233414-A1 | DERIVATIVES OF BODIPY | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233414-A1 | DERIVATIVES OF BODIPY | NPC1L1, NPC1, ABCB4 | MAPT 1353/4885ALDH1A1 2043/4885HPGD 3680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.