SCHEMBL19243141

SCHEMBL19243141

CCc1ccc(OCc2ccccc2)cc1OC

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.57
TDP1 Q9NUW8 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.52
ALOX5 P09917 1/20 0.51
FFAR1 O14842 1/20 0.51
BCHE P06276 2/20 0.49
PDGFRB P09619 1/20 0.49
PDGFRA P16234 1/20 0.49
NPC1 O15118 1/20 0.48
HPGD P15428 1/20 0.48
RAB9A P51151 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ABCB1 P08183 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19339283 0.90 ALOX5 (0.54) MAOBL3MBTL1ALOX5BCHE
SCHEMBL5779644 0.88 MAOB (0.57) MAOBTDP1NPC1HPGDRAB9A
SCHEMBL6035928 0.87 MAOB (0.49) MAOBL3MBTL1ALOX5FFAR1
SCHEMBL13518013 0.86 MAOB (0.55) MAOBTDP1L3MBTL1ALOX5FFAR1
SCHEMBL1097150 0.85 L3MBTL1 (0.61) MAOBTDP1L3MBTL1FFAR1
SCHEMBL4472796 0.85 ALOX5 (0.49) MAOBALOX5
SCHEMBL10998333 0.84 FFAR1 (0.52) MAOBFFAR1NPC1RAB9ASMN1; SMN2
SCHEMBL13973145 0.84 GAA (0.62) MAOBBCHE
SCHEMBL14416964 0.84 MAOB (0.53) MAOBALOX5BCHE
SCHEMBL2173579 0.83 L3MBTL1 (0.58) MAOBTDP1L3MBTL1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9751897-B1 Derivatives of Bodipy OREGON HEALTH & SCIENCE UNIVERSITY (US) 2017-09-05 US disclosed
US-20170233414-A1 DERIVATIVES OF BODIPY OREGON HEALTH & SCIENCE UNIVERSITY (US) 2017-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170233414-A1 DERIVATIVES OF BODIPY NPC1L1, NPC1, ABCB4 MAOB 1280/4885TDP1 1861/4885L3MBTL1 1127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.