Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19250714 | 0.79 | ADORA2A (0.36) | ADORA2AADORA2BTSHR | |
| SCHEMBL16517285 | 0.78 | TDP1 (0.40) | TDP1 | |
| SCHEMBL24121814 | 0.76 | ADORA2A (0.34) | ADORA2AADORA2BTSHR | |
| SCHEMBL16516933 | 0.76 | TDP1 (0.30) | TDP1 | |
| SCHEMBL7260503 | 0.75 | MAPK1 (0.44) | — | |
| SCHEMBL25341013 | 0.73 | — | — | |
| SCHEMBL16516451 | 0.71 | KDM4E (0.52) | — | |
| SCHEMBL18552941 | 0.71 | MEN1 (0.41) | ADORA2AADORA2B | |
| SCHEMBL7256520 | 0.69 | MEN1 (0.47) | TDP1 | |
| SCHEMBL25257054 | 0.68 | MET (0.33) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133665-A1 | 6,7-DIAZAINDAZOLE AND 6,7-DIAZAINDOLE DERIVATIVES AND USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA THEREOF | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |