Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | CA12 | O43570 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | CA9 | Q16790 | 2/20 | 0.61 |
| ▸ | BCHE | P06276 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31177919 | 0.92 | CA1 (0.69) | GAAMAPTCA12CA1CA2 | |
| SCHEMBL11881942 | 0.92 | CA1 (0.69) | GAAMAPTCA12CA1CA2 | |
| SCHEMBL9973111 | 0.90 | MEN1 (0.74) | GAAMAPTMEN1KMT2ATDP1 | |
| SCHEMBL3272134 | 0.90 | GAA (0.91) | GAAMAPTCA12CA1CA2 | |
| SCHEMBL11881258 | 0.90 | GAA (0.91) | GAAMAPTCA12CA1CA2 | |
| SCHEMBL9523764 | 0.89 | SIGMAR1 (0.70) | GAAMAPTBCHEMEN1KMT2A | |
| SCHEMBL9375124 | 0.89 | SIGMAR1 (0.73) | GAAMAPTBCHESIGMAR1CHRM2 | |
| SCHEMBL27228 | 0.88 | GAA (0.95) | GAAMAPTCA12CA1CA2 | |
| SCHEMBL598880 | 0.87 | GAA (0.57) | GAAMAPTCA12CA1CA2 | |
| SCHEMBL597987 | 0.87 | CA1 (0.69) | GAAMAPTCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017137784-A1 | METHOD FOR THE PRODUCTION OF MORPHOLOGICALLY HOMOGENOUS MIRABEGRON AND MIRABEGRON MONOHYDROCHLORIDE | EGIS GYÓGYSZERGYÁR ZRT. (HU) | 2017-08-17 | — | — | WO | disclosed |