Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.73 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.70 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091246 | 0.94 | SIGMAR1 (0.79) | SIGMAR1 | |
| SCHEMBL20689753 | 0.91 | SIGMAR1 (0.72) | SIGMAR1CHRM2 | |
| SCHEMBL9523764 | 0.89 | SIGMAR1 (0.70) | SIGMAR1CHRM2MAOAGAAMAPT | |
| SCHEMBL27071533 | 0.89 | GAA (0.74) | SIGMAR1CHRM2MAOAGAAMAPT | |
| SCHEMBL19245652 | 0.89 | GAA (0.74) | SIGMAR1CHRM2MAOAGAAMAPT | |
| SCHEMBL9973186 | 0.85 | SIGMAR1 (0.75) | SIGMAR1 | |
| SCHEMBL8092471 | 0.85 | SIGMAR1 (1.00) | SIGMAR1CHRM2MAOAGAAMAPT | |
| SCHEMBL7756958 | 0.85 | SIGMAR1 (1.00) | SIGMAR1CHRM2MAOAGAAMAPT | |
| SCHEMBL8097260 | 0.85 | SIGMAR1 (1.00) | SIGMAR1CHRM2MAOAGAAMAPT | |
| SCHEMBL6014369 | 0.85 | SIGMAR1 (1.00) | SIGMAR1CHRM2MAOAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591426-A1 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1994-04-13 | — | — | EP | disclosed |
| WO-1993000313-A2 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1993-01-07 | — | — | WO | disclosed |