Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.30 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5288950 | 0.83 | ALDH1A1 (0.52) | ALDH1A1MAPTPTGS1SLC1A2SLC1A1 | |
| SCHEMBL19246467 | 0.81 | ALDH1A1 (0.42) | ALDH1A1MAPTPTGS1SLC1A2SLC1A1 | |
| SCHEMBL24015558 | 0.80 | ALDH1A1 (0.45) | ALDH1A1MAPTPTGS1SLC1A2SLC1A1 | |
| SCHEMBL20663432 | 0.80 | ALDH1A1 (0.40) | ALDH1A1MAPTPTGS1SLC1A2SLC1A1 | |
| SCHEMBL10443781 | 0.76 | ALDH1A1 (0.45) | ALDH1A1MAPTPTGS1SLC1A2SLC1A1 | |
| SCHEMBL24932482 | 0.74 | ALDH1A1 (0.36) | ALDH1A1MAPTPTGS1 | |
| SCHEMBL24932653 | 0.73 | ALDH1A1 (0.35) | ALDH1A1MAPTPTGS1 | |
| SCHEMBL1237496 | 0.73 | ALDH1A1 (0.50) | ALDH1A1MAPTPTGS1SLC1A2SLC1A1 | |
| SCHEMBL1237494 | 0.73 | ALDH1A1 (0.50) | ALDH1A1MAPTPTGS1SLC1A2SLC1A1 | |
| SCHEMBL1769263 | 0.70 | PTGS1 (0.52) | ALDH1A1MAPTPTGS1SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981908-B2 | Amino acid derivatives | MEDIMMUNE LIMITED (GB) | 2018-05-29 | — | — | US | disclosed |
| US-9732367-B2 | Cell lines | MEDIMMUNE LIMITED (GB) | 2017-08-15 | — | — | US | disclosed |