Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 3/20 | 0.44 |
| ▸ | MMP9 | P14780 | 3/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.44 |
| ▸ | MMP3 | P08254 | 2/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SDCBP | O00560 | 3/20 | 0.41 |
| ▸ | SDC2 | P34741 | 3/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19248316 | 1.00 | LMNA (0.46) | LMNAGAAHPGDSMN1; SMN2MMP2 | |
| SCHEMBL6489465 | 0.81 | MTNR1A (0.42) | LMNASMN1; SMN2ADAMTS4MMEMTNR1A | |
| SCHEMBL7805609 | 0.81 | MTNR1A (0.42) | LMNASMN1; SMN2ADAMTS4MMEMTNR1A | |
| SCHEMBL6489470 | 0.81 | MTNR1A (0.42) | LMNASMN1; SMN2ADAMTS4MMEMTNR1A | |
| SCHEMBL11756343 | 0.74 | MAPT (0.60) | LMNAGAAADAMTS4ALDH1A1 | |
| SCHEMBL9912493 | 0.73 | TDP1 (0.42) | LMNAGAAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL2159141 | 0.71 | LMNA (0.59) | LMNAGAAHPGDSMN1; SMN2MMP2 | |
| SCHEMBL8745550 | 0.71 | LMNA (0.59) | LMNAGAAHPGDSMN1; SMN2MMP2 | |
| SCHEMBL2159137 | 0.71 | LMNA (0.59) | LMNAGAAHPGDSMN1; SMN2MMP2 | |
| SCHEMBL4560594 | 0.70 | MME (0.42) | ALDH1A1MMEMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2409569-B1 | Method for administering GLP-1 molecules | EMISPHERE TECH INC (US) | 2017-08-16 | — | — | EP | disclosed |