Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15294706 | 0.78 | HPGD (0.41) | TDP1MAPTHPGDALDH1A1LMNA | |
| SCHEMBL7805609 | 0.76 | MTNR1A (0.42) | SMN1; SMN2LMNAL3MBTL1TSHRMTNR1A | |
| SCHEMBL6489465 | 0.76 | MTNR1A (0.42) | SMN1; SMN2LMNAL3MBTL1TSHRMTNR1A | |
| SCHEMBL6489470 | 0.76 | MTNR1A (0.42) | SMN1; SMN2LMNAL3MBTL1TSHRMTNR1A | |
| SCHEMBL12487706 | 0.74 | SIGMAR1 (0.57) | CYP3A4TSHR | |
| SCHEMBL22219857 | 0.74 | HDAC4 (0.39) | TDP1SMN1; SMN2MAPTHPGDALDH1A1 | |
| SCHEMBL18757779 | 0.74 | CYP3A4 (0.41) | TDP1MAOAMAPTALDH1A1LMNA | |
| SCHEMBL19370719 | 0.74 | SMN1; SMN2 (0.46) | MAOAMAOBSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL19248314 | 0.73 | LMNA (0.46) | SMN1; SMN2HPGDALDH1A1LMNAMTNR1A | |
| SCHEMBL19248316 | 0.73 | LMNA (0.46) | SMN1; SMN2HPGDALDH1A1LMNAMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198458-B2 | Non-nucleoside reverse transcriptase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-12 | — | — | US | disclosed |