Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.43 |
| ▸ | CSF1R | P07333 | 2/20 | 0.43 |
| ▸ | RET | P07949 | 2/20 | 0.43 |
| ▸ | MET | P08581 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 2/20 | 0.43 |
| ▸ | FLT3 | P36888 | 2/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.43 |
| ▸ | CDK8 | P49336 | 2/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.43 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.43 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PAK4 | O96013 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30936174 | 0.83 | CYP11B1 (0.49) | NPC1RAB9ATP53PKMSMN1; SMN2 | |
| SCHEMBL27018665 | 0.81 | GRIA2 (0.42) | NPC1AURKANTRK1CSF1RRET | |
| SCHEMBL19248551 | 0.80 | KIF11 (0.46) | NPC1RAB9AAURKANTRK1CSF1R | |
| SCHEMBL25247206 | 0.79 | HSD17B10 (0.61) | NPC1RAB9AMAP4K4TP53PKM | |
| SCHEMBL22198919 | 0.79 | DAPK3 (0.47) | NPC1RAB9AAURKANTRK1CSF1R | |
| SCHEMBL29890135 | 0.78 | HSD17B1 (0.45) | NPC1PIM1GSK3BGRIA2RXFP1 | |
| SCHEMBL16045003 | 0.78 | IDH1 (0.41) | NPC1RAB9AAURKANTRK1CSF1R | |
| SCHEMBL3500816 | 0.78 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2GRIA2CASP3 | |
| SCHEMBL23249856 | 0.78 | HSD17B1 (0.45) | NPC1PIM1GSK3BGRIA2RXFP1 | |
| SCHEMBL15040982 | 0.77 | AURKA (0.58) | NPC1RAB9AAURKANTRK1CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9859511-B2 | Organoiridium complex for organic electroluminescent elements | TANAKA KIKINZOKU KOGYO K.K. (JP) | 2018-01-02 | — | — | US | disclosed |
| US-20170237021-A1 | ORGANIC IRIDIUM COMPLEX FOR ORGANIC ELECTROLUMINESCENT ELEMENTS | TANAKA KIKINZOKU KOGYO K.K. (JP) | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170237021-A1 | ORGANIC IRIDIUM COMPLEX FOR ORGANIC ELECTROLUMINESCENT ELEMENTS | L1CAM, ETFA, TTI2 | NPC1 2548/4885RAB9A 4465/4885AURKA 1196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.