Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | HPGD | P15428 | 7/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19248871 | 0.83 | DRD4 (0.50) | GHSRALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL9183301 | 0.82 | GHSR (0.71) | GHSRALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL13234528 | 0.81 | GHSR (0.65) | GHSRALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL19211150 | 0.81 | GHSR (0.65) | GHSRALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL3011498 | 0.81 | GHSR (0.65) | GHSRALDH1A1HPGDKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL19211229 | 0.80 | GHSR (0.64) | GHSRALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL3021147 | 0.78 | AKR1C2 (0.61) | GHSRALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL31587796 | 0.78 | GHSR (0.90) | GHSRALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL20605617 | 0.74 | ALDH1A1 (1.00) | GHSRALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL12285334 | 0.73 | ALDH1A1 (0.69) | GHSRALDH1A1HPGDKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017139274-A1 | QUINOLINONE LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. (US) | 2017-08-17 | — | — | WO | disclosed |