SCHEMBL1924933

SCHEMBL1924933

O=S(=O)(O)c1c(C2CCCCC2)cccc1C1CCCCC1.[NaH]

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.43
PTGDR2 Q9Y5Y4 1/20 0.41
CEL P19835 2/20 0.39
KMO O15229 1/20 0.38
HDAC4 P56524 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HSP90AA1 P07900 1/20 0.35
PTPN5 P54829 2/20 0.35
PTPN2 P17706 1/20 0.35
PTPRC P08575 1/20 0.34
PTPRF P10586 1/20 0.34
PTPN1 P18031 1/20 0.34
CDC25B P30305 1/20 0.34
FFAR2 O15552 1/20 0.34
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
KMT2A Q03164 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2758377 0.98 PTGS2 (0.44) PTGS2PTGDR2CELKMOHDAC4
SCHEMBL4286105 0.86 PTGS2 (0.42) PTGS2PTGDR2CELALDH1A1LMNA
SCHEMBL2758415 0.84 PTGS2 (0.35) PTGS2PTGDR2CELKMOHDAC4
SCHEMBL9101398 0.81 HSP90AA1 (0.43) PTGS2HSP90AA1MEN1ALDH1A1POLB
SCHEMBL2758450 0.80 CYP1B1 (0.41) PTGS2MEN1ALDH1A1KMT2A
SCHEMBL15189417 0.80 PTGS2 (0.38) PTGS2PTGDR2CELPTPN5FFAR2
SCHEMBL2317192 0.80 KMO (0.37) PTGS2KMOHDAC4HDAC2HDAC8
SCHEMBL2758385 0.78 KMO (0.38) PTGS2KMOHDAC4HDAC2HDAC8
SCHEMBL4279326 0.78 PTGS2 (0.46) PTGS2PTGDR2KMOPTPRCPTPRF
SCHEMBL683462 0.78 KMO (0.38) PTGS2KMOHDAC4HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8900791-B2 Actinic ray-sensitive or radiation-sensitive resin composition and method of forming pattern with the composition FUJIFILM CORPORATION (JP) 2014-12-02 US disclosed
US-20110171577-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD OF FORMING PATTERN WITH THE COMPOSITION FUJIFILM CORPORATION (JP) 2011-07-14 US disclosed
EP-2328864-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD OF FORMING PATTERN WITH THE COMPOSITION FUJIFILM Corporation (JP) 2011-06-08 EP disclosed
WO-2010035905-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD OF FORMING PATTERN WITH THE COMPOSITION FUJIFILM CORPORATION (JP) 2010-04-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110171577-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD OF FORMING PATTERN WITH THE COMPOSITION ARSA, RAD51, ARID2 PTGS2 3371/4885PTGDR2 3876/4885CEL 4546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.