SCHEMBL2758415

SCHEMBL2758415

O=S(=O)(O)c1c(C2CCCC(C3CCCCC3)C2)cccc1C1CCCC(C2CCCCC2)C1

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.35
PTGDR2 Q9Y5Y4 1/20 0.33
KMO O15229 1/20 0.33
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32
DRD2 P14416 1/20 0.30
HTR6 P50406 1/20 0.30
HDAC4 P56524 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
CEL P19835 1/20 0.30
EPHX2 P34913 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2758377 0.85 PTGS2 (0.44) PTGS2PTGDR2KMOLMNAHTT
SCHEMBL1924933 0.84 PTGS2 (0.43) PTGS2PTGDR2KMOLMNAHTT
SCHEMBL4286105 0.75 PTGS2 (0.42) PTGS2PTGDR2LMNAHTTHTR6
SCHEMBL19853088 0.74
SCHEMBL29209122 0.71 PTPN5 (0.32) HDAC4HDAC2HDAC8MEN1KMT2A
SCHEMBL29209121 0.71 PTPN5 (0.32) HDAC4HDAC2HDAC8MEN1KMT2A
SCHEMBL9101398 0.71 HSP90AA1 (0.43) PTGS2LMNAHTTEPHX2MEN1
SCHEMBL2758450 0.70 CYP1B1 (0.41) PTGS2EPHX2MEN1KMT2A
SCHEMBL15189417 0.70 PTGS2 (0.38) PTGS2PTGDR2DRD2HTR6CEL
SCHEMBL9099602 0.69 HSD11B1 (0.38) PTGS2PTGDR2LMNAHTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8900791-B2 Actinic ray-sensitive or radiation-sensitive resin composition and method of forming pattern with the composition FUJIFILM CORPORATION (JP) 2014-12-02 US disclosed
US-8900791-B2 Actinic ray-sensitive or radiation-sensitive resin composition and method of forming pattern with the composition FUJIFILM CORPORATION (JP) 2014-12-02 US disclosed
US-20120003585-A1 ACTINIC-RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD OF FORMING PATTERN USING THE COMPOSITION FUJIFILM CORPORATION (JP) 2012-01-05 US disclosed
US-20110171577-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD OF FORMING PATTERN WITH THE COMPOSITION FUJIFILM CORPORATION (JP) 2011-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110171577-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD OF FORMING PATTERN WITH THE COMPOSITION ARSA, RAD51, ARID2 PTGS2 3371/4885PTGDR2 3876/4885KMO 2558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.