Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6655677 | 0.84 | MMP8 (0.48) | MMP8ALDH1A1SLC6A4TSHRACACB | |
| SCHEMBL5326604 | 0.81 | MMP8 (0.53) | MMP8NPY1RNPY2RALDH1A1TP53 | |
| SCHEMBL2050344 | 0.81 | MMP8 (0.53) | MMP8NPY1RNPY2RALDH1A1TP53 | |
| SCHEMBL7696784 | 0.79 | ESR1 (0.51) | MMP8NPY1RNPY2RALDH1A1TP53 | |
| SCHEMBL901733 | 0.78 | EPHX2 (0.50) | MMP8NPY1RNPY2RALDH1A1TP53 | |
| SCHEMBL3764833 | 0.78 | MMP8 (0.50) | MMP8NPY1RNPY2RALDH1A1TP53 | |
| SCHEMBL2426124 | 0.78 | MMP8 (0.54) | MMP8NPY1RNPY2RALDH1A1TP53 | |
| SCHEMBL2429506 | 0.78 | PPARG (0.50) | MMP8NPY1RNPY2RALDH1A1TP53 | |
| SCHEMBL856250 | 0.77 | MMP8 (0.69) | MMP8NPY1RNPY2RALDH1A1TP53 | |
| SCHEMBL19249371 | 0.77 | L3MBTL1 (0.46) | MMP8ALDH1A1TP53PKMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136871-A9 | INDOLE AND AZAINDOLE HALOALLYLAMINE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | PHARMAXIS LTD. (AU) | 2018-02-15 | — | — | WO | disclosed |
| WO-2017136871-A1 | INDOLE AND AZAINDOLE HALOALLYLAMINE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | PHARMAXIS LTD. (AU) | 2017-08-17 | — | — | WO | disclosed |