SCHEMBL19249596

SCHEMBL19249596

Fc1cc(F)c2[nH]nc(I)c2c1

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.39
AR P10275 1/20 0.32
APOL1 O14791 1/20 0.31
EGFR P00533 1/20 0.31
DAO P14920 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27221751 0.82 AR (0.35) AR
SCHEMBL38661124 0.81 PDPK1 (0.31)
SCHEMBL19204854 0.81 AR (0.35) AR
SCHEMBL19204853 0.81 ADORA2A (0.32)
SCHEMBL22890172 0.81 CHEK1 (0.34)
SCHEMBL786095 0.78 GPR84 (0.40) GPR84AREGFRDAO
SCHEMBL31411446 0.77 TAAR1 (0.36)
SCHEMBL19204842 0.77 TTR (0.32)
SCHEMBL31358045 0.77 DHODH (0.33)
SCHEMBL13122194 0.76 ADORA2A (0.49) GPR84AREGFRDAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735425-A1 COMPOUNDS Psylo Pty Ltd (AU) 2026-05-06 EP disclosed
US-20250353818-A1 Compounds Psylo Pty Ltd (AU) 2025-11-20 US disclosed
US-12428380-B2 Compounds Psylo Pty Ltd (AU) 2025-09-30 US disclosed
US-20250214943-A1 Compounds Psylo Pty Ltd (AU) 2025-07-03 US disclosed
WO-2025000053-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-01-02 WO disclosed
WO-2024259241-A1 5-HT2A RECEPTOR MODULATORS AND METHODS OF USE THEREOF Transneural Therapeutics, Inc. (US) 2024-12-19 WO disclosed
EP-3609883-B1 FLUORINE-SUBSTITUTED INDAZOLE COMPOUNDS AND USES THEREOF SUNSHINE LAKE PHARMA CO LTD (CN) 2022-06-29 EP disclosed
US-11242335-B2 Fluorine-substituted indazole compounds and uses thereof SUNSHINE LAKE PHARMA CO., LTD. (CN) 2022-02-08 US disclosed
US-20210101882-A1 FLUORINE-SUBSTITUTED INDAZOLE COMPOUNDS AND USES THEREOF SUNSHINE LAKE PHARMA CO., LTD. (CN) 2021-04-08 US disclosed
CN-108727340-B Fluorine substituted indazoles and use thereof 广东东阳光药业有限公司 2020-12-29 CN disclosed
WO-2017133664-A1 BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA SAVIRA PHARMACEUTICALS GMBH (AT) 2017-08-10 WO disclosed
WO-2017133670-A1 PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA SAVIRA PHARMACEUTICALS GMBH (AT) 2017-08-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214943-A1 Compounds NLN, SLC18A2, PYGB GPR84 3280/4885AR 3574/4885APOL1 4428/4885
US-11242335-B2 Fluorine-substituted indazole compounds and uses thereof GUCY1B2, GUCY1A2, PDE3A GPR84 457/4885AR 3227/4885APOL1 4715/4885
US-12428380-B2 Compounds NLN, SLC18A2, PYGB GPR84 3280/4885AR 3574/4885APOL1 4428/4885
US-20250353818-A1 Compounds NLN, SLC18A2, PYGB GPR84 3280/4885AR 3574/4885APOL1 4428/4885
US-20210101882-A1 FLUORINE-SUBSTITUTED INDAZOLE COMPOUNDS AND USES THEREOF PDE3A, PDE3B, PDE5A GPR84 307/4885AR 2666/4885APOL1 4691/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.