Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14363223 | 0.85 | FFAR1 (0.45) | MRGPRX4KMT2ASMN1; SMN2KDM1AFFAR1 | |
| SCHEMBL24302317 | 0.85 | RAB9A (0.44) | KMT2ASMN1; SMN2RAB9ADRD2DRD4 | |
| SCHEMBL8258103 | 0.82 | LMNA (0.50) | MRGPRX4KMT2ASMN1; SMN2RAB9AFFAR1 | |
| SCHEMBL18295344 | 0.82 | SCN4A (0.47) | MRGPRX4KMT2ASMN1; SMN2CARM1AKT1 | |
| SCHEMBL18295365 | 0.82 | SCN4A (0.47) | MRGPRX4KMT2ASMN1; SMN2CARM1AKT1 | |
| SCHEMBL8251559 | 0.81 | MRGPRX4 (0.42) | MRGPRX4KMT2ASMN1; SMN2RAB9AKDM1A | |
| SCHEMBL18702752 | 0.80 | ALDH1A1 (0.41) | KMT2ASMN1; SMN2MGLLABHD6RAB9A | |
| SCHEMBL29502982 | 0.80 | ALDH1A1 (0.41) | KMT2ASMN1; SMN2MGLLABHD6RAB9A | |
| SCHEMBL19618916 | 0.80 | SCN4A (0.50) | MRGPRX4KMT2ASMN1; SMN2FFAR1PPARD | |
| SCHEMBL27212793 | 0.79 | CARM1 (0.36) | KMT2ASMN1; SMN2MGLLABHD6CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170233340-A1 | NOVEL SUBSTITUTED 6,7-DIHYDRO-5H-BENZO[7]ANNULENE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233340-A1 | NOVEL SUBSTITUTED 6,7-DIHYDRO-5H-BENZO[7]ANNULENE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | CYP19A1, ESR1, ESR2 | MRGPRX4 1294/4885KMT2A 2991/4885SMN1; SMN2 4393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.