Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19250197 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KDM4ERECQLSMN1; SMN2LMNA | |
| SCHEMBL23375383 | 0.70 | MEN1 (0.61) | ALDH1A1KDM4ERECQLSMN1; SMN2LMNA | |
| SCHEMBL8695441 | 0.70 | KDM4E (0.51) | ALDH1A1KDM4ERECQLSMN1; SMN2LMNA | |
| SCHEMBL31329665 | 0.69 | ALDH1A1 (0.69) | ALDH1A1KDM4ERECQLSMN1; SMN2LMNA | |
| SCHEMBL5529472 | 0.69 | ALDH1A1 (0.69) | ALDH1A1KDM4ERECQLSMN1; SMN2LMNA | |
| SCHEMBL2770213 | 0.69 | MAPT (0.47) | ALDH1A1KDM4ESMN1; SMN2LMNANR1H2 | |
| SCHEMBL12458283 | 0.68 | ALDH1A1 (0.39) | ALDH1A1KDM4ESMN1; SMN2LMNAPDE4D | |
| SCHEMBL2580162 | 0.68 | ALDH1A1 (0.53) | ALDH1A1KDM4ERECQLSMN1; SMN2LMNA | |
| SCHEMBL2435532 | 0.67 | ALDH1A1 (0.58) | ALDH1A1KDM4ERECQLSMN1; SMN2LMNA | |
| SCHEMBL3287289 | 0.67 | CA12 (0.49) | ALDH1A1KDM4ESMN1; SMN2NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170233412-A1 | INHIBITORS OF HIF PROLYL HYDROXYLASE | MERCK SHARP & DOHME CORP. (US) | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233412-A1 | INHIBITORS OF HIF PROLYL HYDROXYLASE | HIF1AN, HIF1A, EGLN2 | ALDH1A1 291/4885KDM4E 430/4885RECQL 3744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.