Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 9/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19250443 | 0.82 | NR3C2 (0.43) | NR3C2PDE3BPDE3ANR3C1TP53 | |
| SCHEMBL19250277 | 0.80 | NR3C2 (0.39) | NR3C2PDE3BPDE3ANR3C1KCNH2 | |
| SCHEMBL19629922 | 0.79 | NR3C2 (0.41) | NR3C2NR3C1PKMKMT2AMGLL | |
| SCHEMBL19629923 | 0.78 | NR3C2 (0.43) | NR3C2NR3C1PKMKCNH2GAA | |
| SCHEMBL19629924 | 0.78 | NR3C2 (0.40) | NR3C2NR3C1PKMKMT2AKCNH2 | |
| SCHEMBL7977817 | 0.78 | NR3C2 (0.40) | NR3C2NR3C1PKMKMT2AGAA | |
| SCHEMBL23871692 | 0.73 | MAPK14 (0.40) | NR3C2NR3C1MGLLKCNH2 | |
| SCHEMBL23871561 | 0.71 | NR3C2 (0.38) | NR3C2NR3C1MGLLKCNH2 | |
| SCHEMBL619718 | 0.70 | NR3C2 (0.44) | NR3C2NR3C1PKMKMT2AMGLL | |
| SCHEMBL17956629 | 0.69 | NR3C2 (0.37) | NR3C2NR3C1TP53MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017137744-A1 | HETEROCYCLIC COMPOUNDS, IN PARTICULAR 2-OXO-4,4,5,5,6,6,7,7-OCTAHYDROBENZOXAZOLE DERIVATIVES, AND THEIR USE AS ANTIBACTERIAL COMPOUNDS | REDX PHARMA PLC (GB) | 2017-08-17 | — | — | WO | disclosed |