Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 10/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19629922 | 0.85 | NR3C2 (0.41) | NR3C2NR3C1MMP12ALDH1A1MAPT | |
| SCHEMBL19629924 | 0.84 | NR3C2 (0.40) | NR3C2NR3C1MMP12ALDH1A1MAPT | |
| SCHEMBL7977817 | 0.84 | NR3C2 (0.40) | NR3C2NR3C1MMP12ALDH1A1MAPT | |
| SCHEMBL19250267 | 0.78 | NR3C2 (0.39) | NR3C2NR3C1PKMKCNH2PARP1 | |
| SCHEMBL619718 | 0.76 | NR3C2 (0.44) | NR3C2NR3C1MMP12ALDH1A1MAPT | |
| SCHEMBL19250443 | 0.75 | NR3C2 (0.43) | NR3C2NR3C1ALDH1A1PKMPARP1 | |
| SCHEMBL17956618 | 0.75 | THRB (0.36) | NR3C2NR3C1ALDH1A1MAPTPKM | |
| SCHEMBL17956629 | 0.74 | NR3C2 (0.37) | NR3C2NR3C1MAPTPKMKCNH2 | |
| SCHEMBL17956627 | 0.74 | NR3C2 (0.37) | NR3C2NR3C1MAPTPKMKCNH2 | |
| SCHEMBL7977865 | 0.74 | NR3C2 (0.38) | NR3C2NR3C1MMP12ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017199265-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS ANTI-BACTERIAL AGENTS AND METHOD FOR PRODUCTION | BUGWORKS RESEARCH INDIA PVT LTD (IN) | 2017-11-23 | — | — | WO | disclosed |