Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 9/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977817 | 0.85 | NR3C2 (0.40) | NR3C2NR3C1ALDH1A1MAPTPKM | |
| SCHEMBL19629924 | 0.85 | NR3C2 (0.40) | NR3C2NR3C1ALDH1A1MAPTPKM | |
| SCHEMBL19629923 | 0.85 | NR3C2 (0.43) | NR3C2NR3C1ALDH1A1MAPTPKM | |
| SCHEMBL619718 | 0.80 | NR3C2 (0.44) | NR3C2NR3C1ALDH1A1MAPTPKM | |
| SCHEMBL19250267 | 0.79 | NR3C2 (0.39) | NR3C2NR3C1PKMMGLLGAA | |
| SCHEMBL23871561 | 0.75 | NR3C2 (0.38) | NR3C2NR3C1MGLL | |
| SCHEMBL23871692 | 0.75 | MAPK14 (0.40) | NR3C2NR3C1MGLL | |
| SCHEMBL21400918 | 0.73 | NR3C2 (0.42) | NR3C2NR3C1ALDH1A1MAPTPKM | |
| SCHEMBL7977865 | 0.73 | NR3C2 (0.38) | NR3C2NR3C1ALDH1A1MAPTMGLL | |
| SCHEMBL17956618 | 0.71 | THRB (0.36) | NR3C2NR3C1ALDH1A1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458452-B1 | HETEROCYCLIC COMPOUNDS USEFUL AS ANTI-BACTERIAL AGENTS AND METHOD FOR PRODUCTION | BUGWORKS RES INC (US) | 2023-08-30 | — | — | EP | disclosed |
| WO-2017199265-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS ANTI-BACTERIAL AGENTS AND METHOD FOR PRODUCTION | BUGWORKS RESEARCH INDIA PVT LTD (IN) | 2017-11-23 | — | — | WO | disclosed |