Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19252631 | 0.77 | PIK3CD (0.42) | LMNATP53ALDH1A1 | |
| SCHEMBL19252650 | 0.76 | PIK3R1 (0.39) | — | |
| SCHEMBL19251605 | 0.71 | LMNA (0.34) | LMNATP53 | |
| SCHEMBL19252635 | 0.67 | PIK3R1 (0.48) | ALDH1A1 | |
| SCHEMBL14627845 | 0.57 | CA9 (0.42) | LMNATP53ALDH1A1 | |
| SCHEMBL10930503 | 0.56 | CA12 (0.49) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL6903338 | 0.55 | HPGD (0.58) | LMNA | |
| SCHEMBL30367636 | 0.55 | HPGD (0.58) | LMNA | |
| SCHEMBL21933495 | 0.54 | LMNA (0.49) | LMNAALDH1A1 | |
| Hydrogen Sulfide SCHEMBL29165723 | 0.54 | HPGD (0.57) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133655-A1 | BENZOTHIAZINE AND BENZOTHIADIAZINE COMPOUNDS AND PREPARATION AND USE | 浙江大学 | 2017-08-10 | — | — | WO | disclosed |