Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19251432 | 0.71 | LMNA (0.33) | LMNATP53 | |
| SCHEMBL19252650 | 0.61 | PIK3R1 (0.39) | — | |
| SCHEMBL19252631 | 0.61 | PIK3CD (0.42) | LMNATP53MAPTTHRB | |
| SCHEMBL6903338 | 0.56 | HPGD (0.58) | LMNA | |
| SCHEMBL30367636 | 0.56 | HPGD (0.58) | LMNA | |
| Hydrogen Sulfide SCHEMBL29165723 | 0.55 | HPGD (0.57) | LMNA | |
| SCHEMBL21933495 | 0.55 | LMNA (0.49) | LMNA | |
| SCHEMBL24206029 | 0.54 | LMNA (0.44) | LMNA | |
| SCHEMBL24205860 | 0.54 | CYP1A2 (0.44) | LMNAMAPT | |
| SCHEMBL8293514 | 0.54 | LMNA (0.34) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133655-A1 | BENZOTHIAZINE AND BENZOTHIADIAZINE COMPOUNDS AND PREPARATION AND USE | 浙江大学 | 2017-08-10 | — | — | WO | disclosed |