Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 8/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 8/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14627845 | 0.80 | CA9 (0.42) | LMNATP53MAPTMEN1ALDH1A1 | |
| SCHEMBL19252635 | 0.79 | PIK3R1 (0.48) | PIK3CDPIK3R1MAPTMEN1ALDH1A1 | |
| SCHEMBL10930503 | 0.78 | CA12 (0.49) | LMNAMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL19251432 | 0.77 | LMNA (0.33) | LMNATP53ALDH1A1 | |
| SCHEMBL3058371 | 0.70 | GLS (0.40) | MEN1HPGDKMT2APOLBGAA | |
| SCHEMBL17088227 | 0.69 | MEN1 (0.41) | LMNAMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL19251425 | 0.66 | LMNA (0.36) | PIK3CDPIK3R1LMNATP53MAPT | |
| SCHEMBL11333959 | 0.66 | CA9 (0.41) | PIK3CDPIK3R1LMNAMAPTMEN1 | |
| SCHEMBL13763404 | 0.64 | HSD11B1 (0.46) | LMNATP53MAPTALDH1A1POLB | |
| SCHEMBL11745933 | 0.64 | CA9 (0.46) | LMNAMAPTMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133655-A1 | BENZOTHIAZINE AND BENZOTHIADIAZINE COMPOUNDS AND PREPARATION AND USE | 浙江大学 | 2017-08-10 | — | — | WO | disclosed |