SCHEMBL19252417

SCHEMBL19252417

C=C(C)C(=O)OCCOc1ccc(N=Nc2ccc(CCCCCCCCCCCC)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.52
USP2 O75604 1/20 0.52
ALDH1A1 P00352 1/20 0.52
LMNA P02545 1/20 0.52
CYP3A4 P08684 1/20 0.52
MAPK1 P28482 1/20 0.52
CASP1 P29466 1/20 0.52
KMT2A Q03164 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
SLCO1B3 Q9NPD5 1/20 0.52
SLCO1B1 Q9Y6L6 1/20 0.52
POLB P06746 1/20 0.51
APEX1 P27695 1/20 0.51
HTT P42858 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
THRB P10828 3/20 0.49
THRA P10827 2/20 0.49
TSHR P16473 2/20 0.49
PLA2G4A P47712 2/20 0.48
PPARA Q07869 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28385901 1.00 MEN1 (0.52) MEN1USP2ALDH1A1LMNACYP3A4
SCHEMBL17887281 0.97 MEN1 (0.58) MEN1USP2ALDH1A1LMNACYP3A4
SCHEMBL19270844 0.97 MEN1 (0.58) MEN1USP2ALDH1A1LMNACYP3A4
SCHEMBL28880961 0.97 POLB (0.56) MEN1USP2ALDH1A1LMNACYP3A4
SCHEMBL22328167 0.97 POLB (0.56) MEN1USP2ALDH1A1LMNACYP3A4
SCHEMBL16426523 0.93 POLB (0.57) MEN1USP2ALDH1A1LMNACYP3A4
SCHEMBL30915526 0.93 POLB (0.57) MEN1USP2ALDH1A1LMNACYP3A4
SCHEMBL8515776 0.93 POLB (0.57) MEN1USP2ALDH1A1LMNACYP3A4
SCHEMBL67938 0.93 MEN1 (0.59) MEN1USP2ALDH1A1LMNACYP3A4
SCHEMBL14477491 0.89 MEN1 (0.66) MEN1USP2ALDH1A1LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3214068-B1 AZO MONOMER, AND AZO POLYMER PREPARED BY POLYMERIZATION OF AZO MONOMER LG CHEMICAL LTD (KR) 2019-06-05 EP disclosed
US-10173967-B2 Azo monomer, and azo polymer prepared by polymerization of azo monomer LG CHEM, LTD. (KR) 2019-01-08 US disclosed
US-10173967-B2 Azo monomer, and azo polymer prepared by polymerization of azo monomer LG CHEM, LTD. (KR) 2019-01-08 US disclosed
EP-3214068-A1 AZO MONOMER, AND AZO POLYMER PREPARED BY POLYMERIZATION OF AZO MONOMER LG Chem, Ltd. (KR) 2017-09-06 EP disclosed
EP-3214068-A1 AZO MONOMER, AND AZO POLYMER PREPARED BY POLYMERIZATION OF AZO MONOMER LG Chem, Ltd. (KR) 2017-09-06 EP disclosed
US-20170240504-A1 AZO MONOMER, AND AZO POLYMER PREPARED BY POLYMERIZATION OF AZO MONOMER LG CHEM, LTD. (KR) 2017-08-24 US disclosed
US-20170240504-A1 AZO MONOMER, AND AZO POLYMER PREPARED BY POLYMERIZATION OF AZO MONOMER LG CHEM, LTD. (KR) 2017-08-24 US disclosed
US-20170240504-A1 AZO MONOMER, AND AZO POLYMER PREPARED BY POLYMERIZATION OF AZO MONOMER LG CHEM, LTD. (KR) 2017-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170240504-A1 AZO MONOMER, AND AZO POLYMER PREPARED BY POLYMERIZATION OF AZO MONOMER KCNMA1, CRY1, IK MEN1 153/4885USP2 4677/4885ALDH1A1 2048/4885
US-10173967-B2 Azo monomer, and azo polymer prepared by polymerization of azo monomer KCNMA1, CRY1, IK MEN1 153/4885USP2 4677/4885ALDH1A1 2048/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.