Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 17/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 16/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19252647 | 0.83 | PIK3R1 (0.37) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL19252643 | 0.79 | PIK3R1 (0.39) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL19252633 | 0.76 | SLC40A1 (0.37) | PIK3R1PIK3CDSLC40A1THRB | |
| SCHEMBL19252627 | 0.76 | PIK3R1 (0.45) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL19251619 | 0.76 | PIK3CD (0.59) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL29109324 | 0.75 | PIK3CD (0.37) | PIK3R1PIK3CDSLC40A1CACNA1H | |
| SCHEMBL30604516 | 0.75 | PIK3CD (0.37) | PIK3R1PIK3CDSLC40A1CACNA1H | |
| SCHEMBL19251617 | 0.75 | PIK3CD (0.37) | PIK3R1PIK3CDSLC40A1CACNA1H | |
| SCHEMBL30604520 | 0.75 | PIK3CD (0.37) | PIK3R1PIK3CDSLC40A1CACNA1H | |
| SCHEMBL19251635 | 0.75 | PIK3R1 (0.79) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133655-A1 | BENZOTHIAZINE AND BENZOTHIADIAZINE COMPOUNDS AND PREPARATION AND USE | 浙江大学 | 2017-08-10 | — | — | WO | disclosed |