Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 6/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19252631 | 0.80 | PIK3CD (0.42) | LMNATP53MAPTTHRBPIK3CD | |
| SCHEMBL19252625 | 0.76 | PIK3R1 (0.43) | SLC40A1THRBPIK3CDPIK3R1 | |
| SCHEMBL19251432 | 0.73 | LMNA (0.33) | LMNATP53ALDH1A1 | |
| SCHEMBL19251425 | 0.73 | LMNA (0.36) | SLC40A1LMNATP53MAPTTHRB | |
| SCHEMBL19252643 | 0.67 | PIK3R1 (0.39) | LMNAPIK3CDPIK3R1GRM4 | |
| SCHEMBL19251617 | 0.64 | PIK3CD (0.37) | SLC40A1PIK3CDPIK3R1GRM4 | |
| SCHEMBL19252679 | 0.61 | LMNA (0.33) | LMNATP53CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18818661 | 0.61 | SLC40A1 (0.37) | SLC40A1LMNATP53MAPTL3MBTL1 | |
| SCHEMBL19251435 | 0.60 | GRIA2 (0.32) | — | |
| SCHEMBL21933495 | 0.60 | LMNA (0.49) | LMNACYP1A2GAACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133655-A1 | BENZOTHIAZINE AND BENZOTHIADIAZINE COMPOUNDS AND PREPARATION AND USE | 浙江大学 | 2017-08-10 | — | — | WO | disclosed |