Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LYPLA1 | O75608 | 1/20 | 0.34 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.34 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12733617 | 1.00 | MAPT (0.36) | MAPTGAACNR2MEN1KMT2A | |
| SCHEMBL9405800 | 1.00 | MAPT (0.36) | MAPTGAACNR2MEN1KMT2A | |
| SCHEMBL17736127 | 0.96 | CNR2 (0.34) | MAPTGAACNR2MEN1KMT2A | |
| SCHEMBL23618040 | 0.96 | ACHE (0.35) | MAPTGAACNR2MEN1KMT2A | |
| SCHEMBL19985179 | 0.95 | MAPT (0.36) | MAPTGAACNR2MEN1KMT2A | |
| SCHEMBL19985213 | 0.95 | MAPT (0.36) | MAPTGAACNR2MEN1KMT2A | |
| SCHEMBL19985495 | 0.95 | MAPT (0.36) | MAPTGAACNR2MEN1KMT2A | |
| SCHEMBL19985205 | 0.95 | MAPT (0.36) | MAPTGAACNR2MEN1KMT2A | |
| SCHEMBL19985501 | 0.94 | GAA (0.38) | MAPTGAACNR2MEN1KMT2A | |
| SCHEMBL19985518 | 0.94 | GAA (0.38) | MAPTGAACNR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795398-B2 | Liquid-crystalline medium and liquid-crystal display comprising the same and compounds | MERCK PATENT GMBH (DE) | 2023-10-24 | — | — | US | disclosed |
| EP-4261269-A1 | LIQUID-CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2023-10-18 | — | — | EP | disclosed |
| US-20230323207-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2023-10-12 | — | — | US | disclosed |
| US-20230265345-A1 | LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND APPLICATION OF LIQUID CRYSTAL COMPOSITION | BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) | 2023-08-24 | — | — | US | disclosed |
| US-20230045269-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2023-02-09 | — | — | US | disclosed |
| US-11447701-B2 | Liquid-crystalline medium and liquid-crystal display comprising the same and compounds | MERCK PATENT GMBH (DE) | 2022-09-20 | — | — | US | disclosed |
| EP-4015598-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS | Merck Patent GmbH (DE) | 2022-06-22 | — | — | EP | disclosed |
| US-11326102-B2 | Liquid-crystalline medium and liquid-crystal display comprising the same | MERCK PATENT GMBH (DE) | 2022-05-10 | — | — | US | disclosed |
| US-11168255-B2 | Thiophene compound, liquid-crystalline medium and liquid-crystal display comprising the same | MERCK PATENT GMBH (DE) | 2021-11-09 | — | — | US | disclosed |
| US-11060029-B2 | Liquid-crystalline medium and liquid-crystal display comprising the same | MERCK PATENT GMBH (DE) | 2021-07-13 | — | — | US | disclosed |
| US-10774263-B2 | Liquid-crystalline medium and liquid-crystal display comprising the same | MERCK PATENT GMBH (DE) | 2020-09-15 | — | — | US | disclosed |
| US-10774061-B2 | Liquid-crystalline medium and liquid-crystal display comprising the same | MERCK PATENT GMBH (DE) | 2020-09-15 | — | — | US | disclosed |
| US-10364392-B2 | Liquid-crystalline medium and liquid-crystal display comprising the same | MERCK PATENT GMBH (DE) | 2019-07-30 | — | — | US | disclosed |
| US-20190093013-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2019-03-28 | — | — | US | disclosed |
| US-20190031958-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2019-01-31 | — | — | US | disclosed |
| US-10190048-B2 | Liquid-crystalline medium and liquid-crystal display comprising the same | MERCK PATENT GMBH (DE) | 2019-01-29 | — | — | US | disclosed |
| US-20190002430-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2019-01-03 | — | — | US | disclosed |
| US-20180086980-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2018-03-29 | — | — | US | disclosed |
| US-20170292072-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2017-10-12 | — | — | US | disclosed |
| US-20170233652-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190002430-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | NEFM, FES, LSS | MAPT 208/4885GAA 4461/4885CNR2 4632/4885 |
| US-10774061-B2 | Liquid-crystalline medium and liquid-crystal display comprising the same | NEFM, FES, LSS | MAPT 208/4885GAA 4461/4885CNR2 4632/4885 |
| US-11447701-B2 | Liquid-crystalline medium and liquid-crystal display comprising the same and compounds | NEFM, FES, SBDS | MAPT 447/4885GAA 3705/4885CNR2 4627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.