SCHEMBL19253572

SCHEMBL19253572

N#Cc1nc(C#N)[nH]c(=O)n1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.33
LMNA P02545 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
PSMB8 P28062 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL796035 0.76 L3MBTL1 (0.44) PSMB8
SCHEMBL796034 0.76 XDH (0.38) F2LMNAMAPK1HTT
SCHEMBL9781236 0.74 LMNA (0.40) LMNAPSMB8
SCHEMBL19253573 0.70 PSMB8 (0.35) PSMB8
SCHEMBL1993425 0.64 MAPK1 (0.43) F2LMNAMAPK1HTT
SCHEMBL10841972 0.62 USP8 (0.39) PSMB8
SCHEMBL807925 0.62 XDH (0.38) PSMB8
SCHEMBL8744781 0.57
SCHEMBL5692261 0.57
SCHEMBL10820345 0.53 USP8 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10087541-B2 Method of forming a dielectric through electrodeposition on an electrode for a capacitor UNIVERSITY OF TARTU (EE) 2018-10-02 US claimed
US-20170241036-A1 Method of Forming a Dielectric Through Electrodeposition on an Electrode For a Capacitor UNIVERSITY OF TARTU (EE) 2017-08-24 US claimed
US-10087541-B2 Method of forming a dielectric through electrodeposition on an electrode for a capacitor UNIVERSITY OF TARTU (EE) 2018-10-02 US disclosed
US-20170241036-A1 Method of Forming a Dielectric Through Electrodeposition on an Electrode For a Capacitor UNIVERSITY OF TARTU (EE) 2017-08-24 US disclosed