SCHEMBL19254052

SCHEMBL19254052

CCCCOc1cc(O)c(-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)c(O)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.47
LTA4H P09960 3/20 0.44
KDM4E B2RXH2 3/20 0.44
ALDH1A1 P00352 3/20 0.44
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
MAPT P10636 2/20 0.44
HPGD P15428 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
NR5A1 Q13285 1/20 0.43
DHODH Q02127 1/20 0.43
GPR84 Q9NQS5 1/20 0.43
CYP1A2 P05177 2/20 0.42
CYP2C19 P33261 2/20 0.42
GAA P10253 1/20 0.42
BCHE P06276 1/20 0.42
ACHE P22303 1/20 0.42
HSD17B10 Q99714 1/20 0.41
CYP2D6 P10635 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19240509 0.95 CNR2 (0.51) CNR2NR5A1
SCHEMBL19206304 0.87 ALDH1A1 (0.49) KDM4EALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL19240520 0.86 FFAR1 (0.43) CNR2ALDH1A1L3MBTL1GAA
SCHEMBL19393431 0.86 CNR2 (0.46) CNR2NPC1RAB9AMAPTNR5A1
SCHEMBL29378637 0.86 PTPN11 (0.48) CNR2LTA4HKDM4EALDH1A1NPC1
SCHEMBL1467779 0.86 PTPN11 (0.48) CNR2LTA4HKDM4EALDH1A1NPC1
SCHEMBL6057276 0.86 PTPN11 (0.48) CNR2LTA4HKDM4EALDH1A1NPC1
SCHEMBL17920219 0.86 PTPN11 (0.48) CNR2LTA4HKDM4EALDH1A1NPC1
SCHEMBL19240512 0.85 CNR2 (0.48) CNR2
SCHEMBL19240507 0.84 CNR2 (0.44) CNR2KDM4EALDH1A1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170233551-A1 ULTRAVIOLET ABSORBER AND SYNTHETIC RESIN COMPOSITION ADEKA CORPORATION (JP) 2017-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170233551-A1 ULTRAVIOLET ABSORBER AND SYNTHETIC RESIN COMPOSITION RER1, XRCC5, REV1 CNR2 2920/4885LTA4H 1316/4885KDM4E 860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.