Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15066435 | 0.88 | AKR1B1 (0.41) | AKR1B1ALDH1A1HPGDPOLBNPC1 | |
| SCHEMBL15066992 | 0.81 | AKR1B1 (0.46) | AKR1B1ALDH1A1HPGDPOLBNPC1 | |
| SCHEMBL19254238 | 0.76 | HDAC8 (0.46) | ALDH1A1HPGDCYP2C19CYP2D6KMT2A | |
| SCHEMBL23347656 | 0.75 | AKR1B1 (0.42) | AKR1B1ALDH1A1HPGDPOLBNPC1 | |
| SCHEMBL16054483 | 0.73 | AKR1B1 (0.43) | AKR1B1ALDH1A1HPGDPOLBNPC1 | |
| SCHEMBL9780682 | 0.71 | AKR1B1 (0.52) | AKR1B1ALDH1A1HPGDPOLBCYP2C19 | |
| SCHEMBL9780678 | 0.71 | AKR1B1 (0.52) | AKR1B1ALDH1A1HPGDPOLBCYP2C19 | |
| SCHEMBL2426412 | 0.69 | AKR1B1 (0.43) | AKR1B1ALDH1A1HPGDPOLBCYP2D6 | |
| SCHEMBL15083012 | 0.69 | AKR1B1 (0.43) | AKR1B1ALDH1A1HPGDPOLBCYP2D6 | |
| SCHEMBL16055266 | 0.69 | TRPA1 (0.38) | AKR1B1ALDH1A1HPGDPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797878-B1 | PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING STROKE | BIO-PHARM SOLUTIONS CO LTD (KR) | 2017-08-16 | — | — | EP | disclosed |