SCHEMBL19254239

SCHEMBL19254239

CC(CCc1ccc(Cl)cc1Cl)NC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
POLB P06746 2/20 0.50
GAA P10253 1/20 0.49
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
MAPK1 P28482 1/20 0.47
HDAC8 Q9BY41 2/20 0.46
TAAR1 Q96RJ0 1/20 0.46
HPGD P15428 1/20 0.46
CNR1 P21554 1/20 0.45
METAP2 P50579 2/20 0.45
METAP1 P53582 1/20 0.45
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
ALOX15 P16050 1/20 0.44
CYP2C19 P33261 1/20 0.44
EPHX1 P07099 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23347536 0.80 ATM (0.48) ATML3MBTL1POLBGAAMEN1
SCHEMBL5330701 0.78 ATM (0.71) ATML3MBTL1POLBGAAMEN1
SCHEMBL10587522 0.76 TYR (0.51) ATML3MBTL1POLBGAAMEN1
SCHEMBL436854 0.76 IDO1 (0.50) ATML3MBTL1POLBGAAMEN1
SCHEMBL16054409 0.75 METAP2 (0.48) ATML3MBTL1MEN1KMT2AHPGD
SCHEMBL18568288 0.74 EPHX2 (0.46) POLBGAAMEN1KMT2AHPGD
SCHEMBL4994392 0.73 METAP2 (0.47) ATML3MBTL1GAAHDAC8METAP2
SCHEMBL3529974 0.73 HPGD (0.67) MEN1KMT2ATAAR1HPGDCNR1
SCHEMBL2625213 0.73 PDPK1 (0.51) ATML3MBTL1GAAMAPK1HPGD
SCHEMBL18568295 0.72 POLB (0.40) ATML3MBTL1POLBGAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2797878-B1 PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING STROKE BIO-PHARM SOLUTIONS CO LTD (KR) 2017-08-16 EP disclosed