Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10587522 | 0.85 | TYR (0.51) | IDO1MAPK1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL13995332 | 0.83 | MEN1 (0.53) | IDO1MAPK1MEN1KMT2APOLB | |
| SCHEMBL23718372 | 0.82 | TSHR (0.37) | IDO1MAPK1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL19254203 | 0.82 | SLC6A2 (0.42) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL435685 | 0.81 | SLC6A4 (0.37) | MEN1KMT2APOLBSLC6A2SLC6A4 | |
| SCHEMBL14131063 | 0.81 | TYR (0.51) | IDO1MAPK1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL17834116 | 0.81 | SLC6A2 (0.41) | CYP1A2CYP2C19MEN1KMT2ASLC6A2 | |
| Hydrochloric Acid SCHEMBL5721208 | 0.80 | IDO1 (0.43) | IDO1MAPK1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11621292 | 0.80 | IDO1 (0.65) | IDO1MAPK1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2659771 | 0.79 | IDO1 (0.54) | IDO1MAPK1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11744825-B2 | Methods of treating hypersensitive cough or itching using ion channel inhibitory compounds | AFASCI, INC. (US) | 2023-09-05 | — | — | US | disclosed |
| EP-2968211-B1 | PHENYL ALKYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME | BIO PHARM SOLUTIONS CO LTD (KR) | 2021-05-12 | — | — | EP | disclosed |
| US-10562857-B2 | Ion channel inhibitory compounds, pharmaceutical formulations, and uses | AFASCI, INC. (US) | 2020-02-18 | — | — | US | disclosed |
| US-10525030-B2 | Phenyl carbamate compound and a composition for neuroprotection comprising the same | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2020-01-07 | — | — | US | disclosed |
| US-10323000-B2 | Indole derivatives and their use in neurodegenerative diseases | MERCK PATENT GMBH (DE) | 2019-06-18 | — | — | US | disclosed |
| US-20170355700-A1 | PYRAZOLOPYRIMIDINE ANTIBACTERIAL AGENTS | NORTHERN ILLINOIS RESEARCH FOUNDATION | 2017-12-14 | — | — | US | disclosed |
| US-20170355700-A1 | PYRAZOLOPYRIMIDINE ANTIBACTERIAL AGENTS | NORTHERN ILLINOIS RESEARCH FOUNDATION | 2017-12-14 | — | — | US | disclosed |
| EP-2527314-B1 | Process for preparation of phenyl carbamate derivatives | BIO-PHARM SOLUTIONS CO LTD (KR) | 2017-10-04 | — | — | EP | disclosed |
| EP-2797878-B1 | PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING STROKE | BIO-PHARM SOLUTIONS CO LTD (KR) | 2017-08-16 | — | — | EP | disclosed |
| WO-2017083867-A1 | ION CHANNEL INHIBITORY COMPOUNDS, PHARMACEUTICAL FORMULATIONS AND USES | AFASCI, INC. (US) | 2017-05-18 | — | — | WO | disclosed |
| EP-2797880-B1 | PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY | BIO-PHARM SOLUTIONS CO LTD (KR) | 2017-03-01 | — | — | EP | disclosed |
| US-20160168090-A1 | NOVEL INDOLE DERIVATIVES AND THEIR USE IN NEURODEGENERATIVE DISEASES | MERCK PATENT GMBH (DE) | 2016-06-16 | — | — | US | disclosed |
| EP-2595984-A1 | MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| EP-2595985-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010568-A1 | MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012010567-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| US-20080161288-A1 | COMPOUNDS | PFIZER INC. | 2008-07-03 | — | — | US | disclosed |
| US-7378413-B2 | 2-amino-3-(alkyl)-pyrimidone derivatives | SANOFI AVENTIS (FR) | 2008-05-27 | — | — | US | disclosed |
| US-7378413-B2 | 2-amino-3-(alkyl)-pyrimidone derivatives | SANOFI AVENTIS (FR) | 2008-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168090-A1 | NOVEL INDOLE DERIVATIVES AND THEIR USE IN NEURODEGENERATIVE DISEASES | P2RX3, P2RX7, P2RX2 | IDO1 28/4885MAPK1 2118/4885CYP1A2 1617/4885 |
| US-10562857-B2 | Ion channel inhibitory compounds, pharmaceutical formulations, and uses | CACNA1I, CACNA1G, CACNA1H | IDO1 2136/4885MAPK1 2194/4885CYP1A2 2708/4885 |
| US-11744825-B2 | Methods of treating hypersensitive cough or itching using ion channel inhibitory compounds | TRPV1, TRPA1, TRPV2 | IDO1 920/4885MAPK1 1943/4885CYP1A2 4283/4885 |
| US-10323000-B2 | Indole derivatives and their use in neurodegenerative diseases | P2RX3, ADORA2A, P2RX7 | IDO1 19/4885MAPK1 1995/4885CYP1A2 1409/4885 |
| US-20170355700-A1 | PYRAZOLOPYRIMIDINE ANTIBACTERIAL AGENTS | DHPS, FDPS, IMPDH1 | IDO1 791/4885MAPK1 448/4885CYP1A2 90/4885 |
| US-20080161288-A1 | COMPOUNDS | ADRB2, ADRB1, ADRA2C | IDO1 1788/4885MAPK1 2370/4885CYP1A2 74/4885 |
| US-10525030-B2 | Phenyl carbamate compound and a composition for neuroprotection comprising the same | CHAT, BAX, CASP3 | IDO1 2494/4885MAPK1 2514/4885CYP1A2 3752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.