SCHEMBL23347646

SCHEMBL23347646

CCCc1ccccc1C1OC(=O)N(C)C1O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 2/20 0.34
CYSLTR1 Q9Y271 2/20 0.34
DAO P14920 1/20 0.34
MAOA P21397 1/20 0.33
PRKCG P05129 1/20 0.32
PRKCB P05771 1/20 0.32
PRKCA P17252 1/20 0.32
PRKCH P24723 1/20 0.32
PRKCE Q02156 1/20 0.32
PRKCQ Q04759 1/20 0.32
PRKCD Q05655 1/20 0.32
CES2 O00748 1/20 0.32
CNR2 P34972 3/20 0.32
CNR1 P21554 1/20 0.32
ALDH1A1 P00352 1/20 0.32
ELANE P08246 1/20 0.31
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
CDK4 P11802 1/20 0.30
CCND1 P24385 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18568099 0.82 TSHR (0.34) CYSLTR2CYSLTR1DAOPRKCGPRKCB
SCHEMBL19254483 0.77 MEN1 (0.39) MAOAALDH1A1
SCHEMBL3435945 0.76 KDM4E (0.43) MAOAALDH1A1L3MBTL1
SCHEMBL15083026 0.76 KDM4E (0.43) MAOAALDH1A1L3MBTL1
SCHEMBL15088593 0.72 ALDH1A1 (0.30) ALDH1A1
SCHEMBL3437228 0.68 FFAR1 (0.39) ALDH1A1TDP1L3MBTL1
SCHEMBL3436170 0.68 FFAR1 (0.39) ALDH1A1TDP1L3MBTL1
SCHEMBL3434602 0.68 FFAR1 (0.39) ALDH1A1TDP1L3MBTL1
SCHEMBL3435602 0.66 TSHR (0.41) ALDH1A1L3MBTL1
SCHEMBL28547834 0.63 KDM4E (0.33) CYSLTR2CYSLTR1MAOAALDH1A1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2968211-B1 PHENYL ALKYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME BIO PHARM SOLUTIONS CO LTD (KR) 2021-05-12 EP disclosed