Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 6/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20680892 | 0.80 | PKM (0.45) | ABCC1ABCB1PKMHTTKMT2A | |
| SCHEMBL18038909 | 0.80 | ALDH1A1 (0.49) | ABCC1ABCB1PKMHTTKMT2A | |
| SCHEMBL19239593 | 0.80 | ALDH1A1 (0.42) | ABCC1ABCB1PKMHTTKMT2A | |
| SCHEMBL19086066 | 0.79 | KMT2A (0.39) | ABCC1ABCB1PKMHTTKMT2A | |
| SCHEMBL27020103 | 0.78 | ALDH1A1 (0.41) | ABCC1ABCB1PKMHTTKMT2A | |
| SCHEMBL19337137 | 0.75 | ALDH1A1 (0.41) | ABCC1ABCB1PKMKMT2AMEN1 | |
| SCHEMBL17059202 | 0.75 | PKM (0.46) | ABCC1ABCB1PKMHTTKMT2A | |
| SCHEMBL29823126 | 0.75 | PKM (0.46) | ABCC1ABCB1PKMHTTKMT2A | |
| SCHEMBL29025170 | 0.73 | MAPK1 (0.41) | ABCC1ABCB1PKMHTTKMT2A | |
| SCHEMBL30063515 | 0.73 | MAPT (0.45) | PKMHTTKMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3205650-A1 | EGFR INHIBITOR, AND PREPARATION AND APPLICATION THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2017-08-16 | — | — | EP | disclosed |