Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19086066 | 0.87 | KMT2A (0.39) | ALDH1A1HTTGAALMNAKMT2A | |
| SCHEMBL20680892 | 0.83 | PKM (0.45) | ALDH1A1HTTLMNAKMT2APKM | |
| SCHEMBL18038909 | 0.83 | ALDH1A1 (0.49) | ALDH1A1HTTGAALMNAKMT2A | |
| SCHEMBL19239593 | 0.80 | ALDH1A1 (0.42) | ALDH1A1HTTGAAKMT2APKM | |
| SCHEMBL17059202 | 0.78 | PKM (0.46) | ALDH1A1HTTGAALMNAKMT2A | |
| SCHEMBL29823126 | 0.78 | PKM (0.46) | ALDH1A1HTTGAALMNAKMT2A | |
| SCHEMBL19254677 | 0.78 | ABCC1 (0.39) | ALDH1A1HTTGAALMNAKMT2A | |
| SCHEMBL28836526 | 0.78 | ALDH1A1 (0.52) | ALDH1A1HTTGAALMNAKMT2A | |
| SCHEMBL29025170 | 0.76 | MAPK1 (0.41) | ALDH1A1HTTGAALMNAKMT2A | |
| SCHEMBL30063515 | 0.76 | MAPT (0.45) | ALDH1A1HTTGAAKMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119613383-A | Among the octenib Synthesis method of intermediate | 鲁南制药集团股份有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-114874189-B | Substituted heteroaryl derivatives, compositions and uses thereof | 深圳市塔吉瑞生物医药有限公司 | 2023-09-29 | — | — | CN | disclosed |
| WO-2022166916-A1 | SUBSTITUTED HETEROARYL DERIVATIVE, AND COMPOSITION AND USE THEREOF | 深圳市塔吉瑞生物医药有限公司 | 2022-08-11 | — | — | WO | disclosed |
| CN-114874189-A | Substituted heteroaryl derivatives, compositions and uses thereof | 深圳市塔吉瑞生物医药有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-109485638-B | Preparation method of oxitinib intermediate | 新发药业有限公司 | 2020-07-17 | — | — | CN | disclosed |
| CN-106366072-A | Preparation method of AZD9291 | 上海工程技术大学 | 2017-02-01 | — | — | CN | disclosed |
| CN-106366022-A | Intermediate used for AZD9291 preparation, and preparation method and application thereof | 上海工程技术大学 | 2017-02-01 | — | — | CN | disclosed |