SCHEMBL19254736

SCHEMBL19254736

C[C@H](O)C(OC(N)=O)c1c(Cl)cccc1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCL8 P10145 1/20 0.36
POLB P06746 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
TSHR P16473 2/20 0.35
FEN1 P39748 1/20 0.34
ALOX5 P09917 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2D6 P10635 2/20 0.33
LMNA P02545 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
CYP3A4 P08684 1/20 0.33
NFKB1 P19838 1/20 0.33
ALDH1A1 P00352 1/20 0.33
PNMT P11086 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ADA P00813 1/20 0.33
NOTUM Q6P988 1/20 0.33
BLM P54132 1/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3437319 1.00 CXCL8 (0.36) CXCL8POLBSMN1; SMN2TSHRFEN1
SCHEMBL10119652 1.00 CXCL8 (0.36) CXCL8POLBSMN1; SMN2TSHRFEN1
SCHEMBL10119590 1.00 CXCL8 (0.36) CXCL8POLBSMN1; SMN2TSHRFEN1
SCHEMBL14477703 0.87 CXCL8 (0.35) CXCL8POLBSMN1; SMN2TSHRALOX5
SCHEMBL14477709 0.87 CXCL8 (0.35) CXCL8POLBSMN1; SMN2TSHRALOX5
SCHEMBL14477705 0.87 CXCL8 (0.35) CXCL8POLBSMN1; SMN2TSHRALOX5
SCHEMBL16067624 0.87 CXCL8 (0.36) CXCL8POLBSMN1; SMN2TSHRALOX5
SCHEMBL15078589 0.87 CXCL8 (0.36) CXCL8POLBSMN1; SMN2TSHRALOX5
SCHEMBL19254737 0.84 TAS1R3 (0.37) POLBCYP2D6LMNACYP3A4ALDH1A1
SCHEMBL3435771 0.84 TAS1R3 (0.37) POLBCYP2D6LMNACYP3A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2797878-B1 PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING STROKE BIO-PHARM SOLUTIONS CO LTD (KR) 2017-08-16 EP disclosed