SCHEMBL1925493

SCHEMBL1925493

N#Cc1ccc(N(Cc2ccccc2)C(=O)O)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.73
MEN1 O00255 1/20 0.73
KMT2A Q03164 1/20 0.73
SNCA P37840 1/20 0.55
LTB4R2 Q9NPC1 1/20 0.51
CHRM2 P08172 2/20 0.50
CHRM1 P11229 2/20 0.50
CHRM3 P20309 2/20 0.50
ALDH1A1 P00352 1/20 0.50
GLA P06280 1/20 0.50
HTT P42858 1/20 0.50
RAB9A P51151 1/20 0.50
PAX8 Q06710 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
TAS2R14 Q9NYV8 1/20 0.50
KDM1A O60341 1/20 0.49
SIGMAR1 Q99720 2/20 0.49
TMEM97 Q5BJF2 1/20 0.49
NR3C1 P04150 1/20 0.48
PGR P06401 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7320662 0.85 NPC1 (0.63) NPC1MEN1KMT2ASNCALTB4R2
SCHEMBL7323824 0.85 NPC1 (0.63) NPC1MEN1KMT2ASNCALTB4R2
SCHEMBL6429962 0.83 NPC1 (0.68) NPC1MEN1KMT2ASNCALTB4R2
SCHEMBL10532358 0.83 NPC1 (0.59) NPC1MEN1KMT2ASNCALTB4R2
SCHEMBL1927016 0.82 ALDH1A1 (0.69) NPC1MEN1KMT2AALDH1A1GLA
SCHEMBL6802291 0.80 MEN1 (0.76) NPC1MEN1KMT2ASNCALTB4R2
SCHEMBL15899250 0.80 NPC1 (0.56) NPC1MEN1KMT2ASNCALTB4R2
SCHEMBL3059431 0.80 MEN1 (0.59) NPC1MEN1KMT2ALTB4R2
SCHEMBL3611701 0.79 NSD2 (0.54) NPC1MEN1KMT2APOLB
SCHEMBL27565502 0.79 MEN1 (0.74) NPC1MEN1KMT2ASNCALTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1300407-B2 CARBAMATES DERIVED FROM ARYLALKYLAMINES S A L V A T LAB SA (ES) 2011-06-08 EP claimed