Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | NPC1 | O15118 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.76 |
| ▸ | PDK1 | Q15118 | 6/20 | 0.60 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.60 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.60 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.60 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.50 |
| ▸ | PTGES | O14684 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6799435 | 0.93 | MEN1 (0.72) | MEN1NPC1KMT2APDK1PDK2 | |
| SCHEMBL27565502 | 0.88 | MEN1 (0.74) | MEN1NPC1KMT2APDK1PDK2 | |
| SCHEMBL6799801 | 0.86 | GAA (0.62) | MEN1NPC1KMT2APDK1PDK2 | |
| SCHEMBL6798512 | 0.83 | MEN1 (0.55) | MEN1NPC1KMT2APDK1PDK2 | |
| SCHEMBL6800721 | 0.81 | MEN1 (0.63) | MEN1NPC1KMT2APDK1PDK2 | |
| SCHEMBL6800779 | 0.80 | MEN1 (0.55) | MEN1NPC1KMT2APDK1PDK2 | |
| SCHEMBL1925493 | 0.80 | NPC1 (0.73) | MEN1NPC1KMT2ALTB4R2ALDH1A1 | |
| SCHEMBL6801305 | 0.77 | CYP19A1 (0.55) | MEN1NPC1KMT2APDK1PDK2 | |
| SCHEMBL10579072 | 0.77 | MEN1 (0.66) | MEN1NPC1KMT2APDK1PDK2 | |
| SCHEMBL8332050 | 0.76 | KMT2A (0.71) | MEN1NPC1KMT2APDK1LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1308297-C | Phenyl sulfamate derivs. | TEIKOKU HORMONE MFG CO LTD (JP) | 2007-04-04 | — | — | CN | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| CN-1360570-A | Phenyl sulfamate derivs. | TEIKOKU HORMONE MFG CO LTD (JP) | 2002-07-24 | — | — | CN | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |