SCHEMBL19254992

SCHEMBL19254992

CN(C(=O)c1cnc(C(=O)NS(C)(=O)=O)n1C)c1cccnc1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.39
NOTUM Q6P988 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
GAA P10253 1/20 0.36
HPGD P15428 1/20 0.36
LMNA P02545 1/20 0.35
NAMPT P43490 4/20 0.35
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GRM5 P41594 2/20 0.33
PYGL P06737 1/20 0.33
MLYCD O95822 1/20 0.33
EGFR P00533 1/20 0.33
PTGS2 P35354 1/20 0.33
P4HTM Q9NXG6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19211888 0.83 TRPV1 (0.44) TRPV1NOTUMGAANAMPTGRM5
SCHEMBL19254991 0.83 NAMPT (0.54) L3MBTL1LMNANAMPTALDH1A1SMN1; SMN2
SCHEMBL20733023 0.83 TRPV1 (0.44) TRPV1NOTUMGAAHPGDNAMPT
SCHEMBL19255739 0.83 NAMPT (0.47) NOTUML3MBTL1GAALMNANAMPT
SCHEMBL19211883 0.82 ALDH1A1 (0.43) TRPV1NOTUMGAAHPGDNAMPT
SCHEMBL19254996 0.81 TRPV1 (0.40) TRPV1NOTUMNAMPTGRM5PYGL
SCHEMBL19764033 0.81 TRPV1 (0.42) TRPV1NOTUML3MBTL1GAAHPGD
SCHEMBL20732860 0.80 HTT (0.43) TRPV1GAAHPGDLMNANAMPT
SCHEMBL19211846 0.80 TRPV1 (0.41) TRPV1NOTUMNAMPTMLYCD
SCHEMBL19211797 0.79 NOTUM (0.41) TRPV1NOTUMNAMPTALDH1A1MLYCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3414238-B1 SUBSTITUTED IMIDAZOLYL-CARBOXAMIDES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2021-03-24 EP disclosed
US-10349657-B2 Substituted imidazolylcarboxamides as pesticides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-07-16 US disclosed
US-20190045783-A1 SUBSTITUTED IMIDAZOLYLCARBOXAMIDES AS PESTICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-02-14 US disclosed
WO-2017137319-A1 SUBSTITUTED -OXYIMIDAZOLYL-CARBOXAMIDES AS PEST CONTROL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-08-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190045783-A1 SUBSTITUTED IMIDAZOLYLCARBOXAMIDES AS PESTICIDES DDT, CYCS, TSNAX TRPV1 1427/4885NOTUM 421/4885L3MBTL1 269/4885
US-10349657-B2 Substituted imidazolylcarboxamides as pesticides DDT, CYCS, TSNAX TRPV1 1427/4885NOTUM 421/4885L3MBTL1 269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.