Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19254991 | 0.94 | NAMPT (0.54) | NAMPTALDH1A1SMN1; SMN2KDM1ARCOR1 | |
| SCHEMBL20732860 | 0.84 | HTT (0.43) | NAMPTSMN1; SMN2PKMHTTGAA | |
| SCHEMBL19211888 | 0.83 | TRPV1 (0.44) | NAMPTPKMHTTGAANOTUM | |
| SCHEMBL20733023 | 0.83 | TRPV1 (0.44) | NAMPTHTTGAANOTUM | |
| SCHEMBL19254992 | 0.83 | TRPV1 (0.39) | NAMPTALDH1A1SMN1; SMN2GAANOTUM | |
| SCHEMBL19211883 | 0.82 | ALDH1A1 (0.43) | NAMPTALDH1A1NPC1RAB9AHTT | |
| SCHEMBL19254996 | 0.81 | TRPV1 (0.40) | NAMPTPKMHTTNOTUM | |
| SCHEMBL19211846 | 0.80 | TRPV1 (0.41) | NAMPTHTTNOTUMNPSR1 | |
| SCHEMBL19211797 | 0.79 | NOTUM (0.41) | NAMPTALDH1A1NPC1RAB9AHTT | |
| SCHEMBL19244951 | 0.78 | NOTUM (0.46) | NAMPTALDH1A1NPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414238-B1 | SUBSTITUTED IMIDAZOLYL-CARBOXAMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-03-24 | — | — | EP | disclosed |
| US-10349657-B2 | Substituted imidazolylcarboxamides as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-07-16 | — | — | US | disclosed |
| US-20190045783-A1 | SUBSTITUTED IMIDAZOLYLCARBOXAMIDES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-02-14 | — | — | US | disclosed |
| WO-2017137319-A1 | SUBSTITUTED -OXYIMIDAZOLYL-CARBOXAMIDES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190045783-A1 | SUBSTITUTED IMIDAZOLYLCARBOXAMIDES AS PESTICIDES | DDT, CYCS, TSNAX | NAMPT 3551/4885ALDH1A1 3492/4885SMN1; SMN2 3273/4885 |
| US-10349657-B2 | Substituted imidazolylcarboxamides as pesticides | DDT, CYCS, TSNAX | NAMPT 3551/4885ALDH1A1 3492/4885SMN1; SMN2 3273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.