Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30975876 | 0.77 | — | — | |
| SCHEMBL4013579 | 0.77 | — | — | |
| SCHEMBL5700357 | 0.72 | LMNA (0.40) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL24706910 | 0.72 | KDM4E (0.37) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30080735 | 0.68 | ALDH1A1 (0.41) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL786015 | 0.68 | ALDH1A1 (0.41) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL24758436 | 0.68 | SSTR4 (0.37) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28593937 | 0.67 | EHMT2 (0.65) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4175402 | 0.64 | ALDH1A1 (0.38) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL29457472 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022256702-A1 | SUBSTITUTED TETRAHYDROFURAN-2-CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-12-08 | — | — | WO | disclosed |
| WO-2017136870-A9 | HALOALLYLAMINE INDOLE AND AZAINDOLE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | PHARMAXIS LTD. (AU) | 2018-02-15 | — | — | WO | disclosed |
| WO-2017136870-A1 | HALOALLYLAMINE INDOLE AND AZAINDOLE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | PHARMAXIS LTD. (AU) | 2017-08-17 | — | — | WO | disclosed |