Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6525647 | 0.72 | CYP1A2 (0.46) | ALDH1A1MAPTGAAL3MBTL1TSHR | |
| SCHEMBL3647399 | 0.72 | NPC1 (0.61) | ALDH1A1MAPTL3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL2874801 | 0.72 | NPC1 (0.61) | ALDH1A1MAPTL3MBTL1TSHRSMN1; SMN2 | |
| Hydrogen Sulfide SCHEMBL27801563 | 0.70 | NPC1 (0.59) | ALDH1A1MAPTL3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL21906009 | 0.70 | HSD17B10 (0.50) | ALDH1A1MAPTGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL30841348 | 0.70 | HSD17B10 (0.50) | ALDH1A1MAPTGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL4013579 | 0.69 | — | — | |
| SCHEMBL30975876 | 0.69 | — | — | |
| SCHEMBL4156992 | 0.68 | L3MBTL1 (0.40) | ALDH1A1GAAL3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL10848424 | 0.68 | KDM4E (0.39) | ALDH1A1MAPTGAAL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101541751-A | Quinoline compounds | WYETH CORP (US) | 2009-09-23 | — | — | CN | disclosed |
| EP-2074098-A2 | QUINOLINE COMPOUNDS | Wyeth (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008049047-A2 | QUINOLINE COMPOUNDS | WYETH (US) | 2008-04-24 | — | — | WO | disclosed |