Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 3/20 | 0.54 |
| ▸ | RARB | P10826 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2433889 | 1.00 | PTPN11 (0.54) | PTPN11RARBSMN1; SMN2NPC1LMNA | |
| SCHEMBL11133724 | 0.88 | PTPN11 (0.61) | PTPN11RARBSMN1; SMN2LMNACYP3A4 | |
| SCHEMBL11138404 | 0.88 | PTPN11 (0.61) | PTPN11RARBSMN1; SMN2LMNACYP3A4 | |
| SCHEMBL9511120 | 0.87 | PTPN11 (0.63) | PTPN11RARBTP53TSHRPLA2G4B | |
| SCHEMBL9511529 | 0.87 | PTPN11 (0.63) | PTPN11RARBTP53TSHRPLA2G4B | |
| SCHEMBL1925576 | 0.85 | LMNA (0.63) | RARBSMN1; SMN2NPC1LMNANFKB1 | |
| SCHEMBL2433887 | 0.85 | LMNA (0.63) | RARBSMN1; SMN2NPC1LMNANFKB1 | |
| SCHEMBL28564613 | 0.84 | PLK1 (0.50) | PTPN11RARBSMN1; SMN2NPC1LMNA | |
| SCHEMBL9485504 | 0.82 | RARB (0.62) | PTPN11RARBSMN1; SMN2LMNAMAPT | |
| SCHEMBL7981006 | 0.82 | PTPN11 (0.66) | PTPN11RARBMAPTPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358845-B1 | ALIGNMENT FACILITIES FOR OPTICAL DYES | TRANSITIONS OPTICAL INC (US) | 2014-11-12 | — | — | EP | disclosed |
| US-8828507-B2 | Alignment facilities for optical dyes | TRANSITIONS OPTICAL, INC. (US) | 2014-09-09 | — | — | US | disclosed |
| EP-2358845-A1 | ALIGNMENT FACILITIES FOR OPTICAL DYES | TRANSITIONS OPTICAL, INC. (US) | 2011-08-24 | — | — | EP | disclosed |
| US-8003005-B2 | Alignment facilities for optical dyes | TRANSITIONS OPTICAL, INC. (US) | 2011-08-23 | — | — | US | disclosed |
| US-20110128457-A1 | ALIGNMENT FACILITIES FOR OPTICAL DYES | TRANSITIONS OPTICAL, INC. (US) | 2011-06-02 | — | — | US | disclosed |
| WO-2010065406-A1 | ALIGNMENT FACILITIES FOR OPTICAL DYES | TRANSITIONS OPTICAL, INC. (US) | 2010-06-10 | — | — | WO | disclosed |
| US-20090146104-A1 | ALIGNMENT FACILITIES FOR OPTICAL DYES | TRANSITIONS OPTICAL, INC. (US) | 2009-06-11 | — | — | US | disclosed |