Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | CES2 | O00748 | 6/20 | 0.52 |
| ▸ | CES1 | P23141 | 6/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21761708 | 0.81 | GAA (0.66) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL5998679 | 0.80 | ALDH1A1 (0.61) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL27177997 | 0.80 | MAPT (0.78) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL7752872 | 0.80 | MAPT (0.78) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL12186262 | 0.80 | MAPT (0.78) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL17637926 | 0.80 | CYP1A2 (0.55) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL17642357 | 0.78 | CA2 (0.48) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL17628487 | 0.78 | CA2 (0.48) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL17628493 | 0.77 | KDM4E (0.46) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL17637928 | 0.77 | KDM4E (0.46) | NPC1RAB9AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732042-B2 | Method for producing pyridazine compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-15 | — | — | US | disclosed |