Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19257461 | 0.88 | MAPT (0.33) | TSHRCYP2C9 | |
| SCHEMBL19257463 | 0.86 | THRB (0.43) | THRBUSP2LMNAALDH1A1TSHR | |
| SCHEMBL19257465 | 0.83 | THRB (0.46) | THRBUSP2LMNAALDH1A1PLA2G2C | |
| SCHEMBL19257462 | 0.83 | THRB (0.46) | THRBUSP2LMNAALDH1A1PLA2G2C | |
| SCHEMBL19257460 | 0.83 | CYP2C9 (0.41) | USP2TSHRCYP2C9 | |
| SCHEMBL19257466 | 0.83 | CYP2C9 (0.32) | TSHRCYP2C9 | |
| SCHEMBL26828591 | 0.77 | USP2 (0.48) | USP2LMNAALDH1A1TSHRAGTR1 | |
| SCHEMBL15463132 | 0.76 | USP2 (0.52) | USP2LMNAALDH1A1TSHRCYP2C9 | |
| SCHEMBL316627 | 0.75 | — | — | |
| SCHEMBL10304880 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170233337-A1 | NON-IONIC AMPHIPHILES AND METHODS OF MAKING THE SAME | ARCHER DANIELS MIDLAND CO (IL) | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233337-A1 | NON-IONIC AMPHIPHILES AND METHODS OF MAKING THE SAME | PNLIP, FFAR4, SPTLC2 | THRB 1743/4885USP2 2124/4885LMNA 2175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.