Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20436735 | 0.87 | RECQL (0.41) | FAAHASAH2SMN1; SMN2SLC6A5HRH3 | |
| SCHEMBL26231755 | 0.85 | PLA2G10 (0.38) | FAAHHRH3CAPN1NPSR1 | |
| SCHEMBL25052849 | 0.85 | PLA2G10 (0.38) | FAAHHRH3CAPN1NPSR1 | |
| SCHEMBL25052856 | 0.85 | FAAH (0.49) | FAAHASAH2SMN1; SMN2SLC6A5CAPN1 | |
| SCHEMBL17570956 | 0.84 | RECQL (0.39) | HRH3CAPN1NPSR1 | |
| SCHEMBL17616958 | 0.84 | RECQL (0.39) | HRH3CAPN1NPSR1 | |
| SCHEMBL21549706 | 0.82 | NPSR1 (0.38) | FAAHHRH3CAPN1NPSR1ALDH1A1 | |
| SCHEMBL19257485 | 0.80 | FAAH (0.57) | FAAHASAH2SMN1; SMN2SLC6A5LPAR3 | |
| SCHEMBL28303045 | 0.79 | FAAH (0.60) | FAAHASAH2SMN1; SMN2SLC6A5HRH3 | |
| SCHEMBL28303046 | 0.79 | FAAH (0.60) | FAAHASAH2SMN1; SMN2SLC6A5HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136693-A1 | GCC-TARGETED ANTIBODY-DRUG CONJUGATES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-08-10 | — | — | WO | disclosed |