Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19257482 | 0.87 | FAAH (0.39) | CAPN1FAAHNPSR1HRH3ASAH2 | |
| SCHEMBL21418111 | 0.86 | PSMB5 (0.51) | RECQLGAAPSMB5CAPN1FAAH | |
| SCHEMBL25051421 | 0.86 | RECQL (0.42) | RECQLGAAPSMB5CAPN1FAAH | |
| SCHEMBL22987342 | 0.85 | RECQL (0.53) | RECQLGAAPSMB5CAPN1NPSR1 | |
| SCHEMBL25122213 | 0.85 | RECQL (0.53) | RECQLGAAPSMB5CAPN1NPSR1 | |
| SCHEMBL27175504 | 0.81 | PSMB5 (0.45) | GAAPSMB5FAAHASAH2SMN1; SMN2 | |
| SCHEMBL27175509 | 0.80 | FAAH (0.54) | RECQLGAAPSMB5FAAHSMN1; SMN2 | |
| SCHEMBL27175510 | 0.79 | PSMB5 (0.42) | RECQLGAAPSMB5FAAHASAH2 | |
| SCHEMBL24917447 | 0.79 | RECQL (0.53) | RECQLGAAFAAH | |
| SCHEMBL28339162 | 0.77 | NPSR1 (0.35) | RECQLPSMB5NPSR1HRH3CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018140435-A1 | METHODS OF PREPARING CYTOTOXIC BENZODIAZEPINE DERIVATIVES | IMMUNOGEN, INC. (US) | 2018-08-02 | — | — | WO | disclosed |