SCHEMBL19257502

SCHEMBL19257502

Clc1nc(-c2ccccc2-c2ccccc2)c2ccccc2n1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.58
ALDH1A1 P00352 4/20 0.58
LMNA P02545 4/20 0.49
MAPT P10636 2/20 0.49
HPGD P15428 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
GLA P06280 1/20 0.48
ADORA2A P29274 5/20 0.45
NUDT1 P36639 3/20 0.44
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
KMT2A Q03164 3/20 0.43
OPRK1 P41145 1/20 0.43
PKM P14618 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
GAA P10253 2/20 0.42
HTT P42858 1/20 0.42
PDE5A O76074 1/20 0.41
APP P05067 1/20 0.41
MEN1 O00255 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18646843 0.91 KDM4E (0.57) KDM4EALDH1A1LMNAMAPTHPGD
SCHEMBL15860258 0.89 KDM4E (0.58) KDM4EALDH1A1LMNAMAPTHPGD
SCHEMBL808420 0.85 KDM4E (0.77) KDM4EALDH1A1LMNAMAPTHPGD
SCHEMBL18456304 0.83 KDM4E (0.49) KDM4EALDH1A1LMNAMAPTHPGD
SCHEMBL17299610 0.82 KDM4E (0.59) KDM4EALDH1A1LMNAMAPTHPGD
SCHEMBL29572574 0.82 ALDH1A1 (0.54) KDM4EALDH1A1LMNAMAPTHPGD
SCHEMBL15860268 0.82 ALDH1A1 (0.54) KDM4EALDH1A1LMNAMAPTHPGD
SCHEMBL808191 0.81 KDM4E (0.77) KDM4EALDH1A1LMNAMAPTHPGD
Hydrochloric Acid SCHEMBL5803147 0.81 KDM4E (0.72) KDM4EALDH1A1LMNAMAPTHPGD
SCHEMBL17286874 0.81 KDM4E (0.77) KDM4EALDH1A1LMNAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023160187-A1 CARBAZOLE DERIVATIVE AND USE THEREOF 上海八亿时空先进材料有限公司 2023-08-31 WO disclosed
WO-2022229234-A1 NITROGENOUS HETEROCYCLIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-11-03 WO disclosed
WO-2017146406-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2017-08-31 WO disclosed
WO-2017135717-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2017-08-10 WO disclosed