Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19257220 | 0.89 | HSD17B1 (0.46) | FFAR1HDAC8HDAC3HDAC1NCOR2 | |
| SCHEMBL19257277 | 0.89 | AKR1C3 (0.44) | AKR1C3AKR1C2HDAC8HDAC3HDAC1 | |
| SCHEMBL19257268 | 0.87 | HDAC8 (0.45) | FFAR1HDAC8HDAC3HDAC1NCOR2 | |
| SCHEMBL19257583 | 0.84 | HDAC8 (0.43) | AKR1C3AKR1C2HDAC8HDAC3HDAC1 | |
| SCHEMBL19209497 | 0.82 | P4HB (0.44) | FFAR1HDAC8HDAC3HDAC1NCOR2 | |
| SCHEMBL19257289 | 0.82 | PLAU (0.46) | AKR1C3AKR1C2HDAC8HDAC3HDAC1 | |
| SCHEMBL19257205 | 0.82 | JUN (0.51) | GAA | |
| SCHEMBL3292447 | 0.82 | HDAC8 (0.60) | HDAC8HDAC3HDAC1NCOR2PTGER4 | |
| SCHEMBL3292450 | 0.82 | HDAC8 (0.60) | HDAC8HDAC3HDAC1NCOR2PTGER4 | |
| SCHEMBL19257274 | 0.81 | HDAC8 (0.44) | FFAR1AKR1C3HDAC8HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017134146-A1 | GPBP INHIBITORS AND USES AND SCALEABLE SYNTHESIS THEREOF | FIBROSTATIN, S.L. (ES) | 2017-08-10 | — | — | WO | disclosed |