Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19257560 | 0.88 | POLB (0.46) | POLBHSD17B10FFAR1EGFRPDGFRB | |
| SCHEMBL19257270 | 0.85 | POLB (0.43) | POLBHSD17B10S1PR1FFAR1EGFR | |
| SCHEMBL15602007 | 0.84 | POLB (0.46) | POLBHSD17B10S1PR1FFAR1TDP1 | |
| SCHEMBL19209491 | 0.81 | S1PR1 (0.46) | POLBHSD17B10S1PR1FFAR1 | |
| SCHEMBL19257272 | 0.79 | POLB (0.50) | POLBHSD17B10S1PR1FFAR1EGFR | |
| SCHEMBL16863734 | 0.75 | POLB (0.48) | POLBFFAR1PDGFRBFGFR1KDR | |
| SCHEMBL491188 | 0.75 | HSD17B10 (0.71) | POLBHSD17B10 | |
| SCHEMBL30436820 | 0.75 | HSD17B10 (0.71) | POLBHSD17B10 | |
| SCHEMBL38659657 | 0.74 | POLB (0.50) | POLBHSD17B10S1PR1FFAR1GAA | |
| SCHEMBL1891972 | 0.74 | POLB (0.50) | POLBHSD17B10S1PR1FFAR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017134146-A1 | GPBP INHIBITORS AND USES AND SCALEABLE SYNTHESIS THEREOF | FIBROSTATIN, S.L. (ES) | 2017-08-10 | — | — | WO | disclosed |