Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.42 |
| ▸ | KDR | P35968 | 4/20 | 0.42 |
| ▸ | EGFR | P00533 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19257272 | 0.91 | POLB (0.50) | POLBHSD17B10FFAR1PDGFRBFGFR1 | |
| SCHEMBL19257555 | 0.88 | POLB (0.45) | POLBHSD17B10FFAR1PDGFRBFGFR1 | |
| SCHEMBL1891972 | 0.86 | POLB (0.50) | POLBHSD17B10FFAR1HTTMAPT | |
| SCHEMBL38659657 | 0.86 | POLB (0.50) | POLBHSD17B10FFAR1HTTMAPT | |
| SCHEMBL19209443 | 0.80 | S1PR1 (0.51) | POLBHSD17B10 | |
| SCHEMBL19257588 | 0.80 | HSD17B10 (0.43) | POLBHSD17B10FFAR1MAPT | |
| SCHEMBL12660792 | 0.79 | POLB (0.52) | POLBHSD17B10FFAR1PDGFRBFGFR1 | |
| SCHEMBL15602007 | 0.78 | POLB (0.46) | POLBHSD17B10FFAR1HTT | |
| SCHEMBL15602073 | 0.77 | RAB9A (0.44) | POLBHSD17B10FFAR1MAPT | |
| SCHEMBL491188 | 0.75 | HSD17B10 (0.71) | POLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017134146-A1 | GPBP INHIBITORS AND USES AND SCALEABLE SYNTHESIS THEREOF | FIBROSTATIN, S.L. (ES) | 2017-08-10 | — | — | WO | disclosed |